Novel Type V Staphylococcal Cassette Chromosome mec Driven by a Novel Cassette Chromosome Recombinase, ccrC

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Staphylococcal Cassette Chromosome mec in MRSA, Taiwan

To determine the predominant staphylococcal cassette chromosome (SCC) mec element in methicillin-resistant Staphylococcus aureus, we typed 190 isolates from a hospital in Taiwan. We found a shift from type IV to type III SCCmec element during 1992-2003, perhaps caused by selective pressure from indiscriminate use of antimicrobial drugs.

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Mosaic staphylococcal cassette chromosome mec containing two recombinase loci and a new mec complex, B2.

A novel staphylococcal cassette chromosome (SCC) mec from a clinical methicillin-resistant Staphylococcus aureus isolate (ST100/CC5) had a mosaic structure, composed of SCC DNA from several different backgrounds. It harbored two complete ccr loci and a new variant of mec complex B, with DeltamecR1 interrupted by the aminoglycoside resistance transposon Tn4001.

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Considerations for the distinction of ccrC-containing staphylococcal cassette chromosome mec elements.

Staphylococcal cassette chromosome mec (SCCmec) elements confer methicillin resistance to the human pathogen Staphylococcus aureus (methicillin-resistant S. aureus [MRSA]). Recently, the International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG-SCC) has published new guidelines for classifying different SCCmec elements (3). The new classification of S...

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Molecular Investigation of Staphylococcal Cassette Chromosome mec (SCCmec) Elements Isolated from Intensive Care Unit

Background and Aims: Based on the results, Staphylococcus aureus is one of the serious infectious agents found in community and hospitals with remarkable potential for high morbidity and mortality around the globe. The present study was carried out for molecular investigation of methicillin-resistant Staphylococcus aureus strains and Staphylococcal Chromosomal Cassette mec (SCCmec) phenotypes i...

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Staphylococcus aureus CC395 harbours a novel composite staphylococcal cassette chromosome mec element

Background CoNS species are likely reservoirs of the staphylococcal cassette chromosome mec (SCC mec ) in Staphylococcus aureus . S . aureus CC395 is unique as it is capable of exchanging DNA with CoNS via bacteriophages, which are also known to mediate transfer of SCC mec . Objectives To analyse the structure and putative origin of the SCC mec element in S . aureus CC395. Methods The only ...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2004

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.48.7.2637-2651.2004